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Psychological dependence is a state that involves emotional–motivational withdrawal symptoms, e.g. anxiety and anhedonia, upon cessation of drug use or certain behaviours. It develops through frequent exposure to a psychoactive substance or behaviour, though behavioural dependence is less talked about. The specific mechanism involves a neuronal counter-adaption, which could be mediated through changes in neurotransmittor activity or altered receptor expression. Withdrawal symptoms can be attenuated by environmental enrichment and physical activity. Psychological dependence is not to be confused with physical dependence, which induces physical withdrawal symptoms upon discontinuation of use. However they are not mutually exclusive.

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psycholeptic, psychologer, psychologian, psychologic, psychological, psychologically, psychologics, psychologism, psychologist, psychologize

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"psychological dependence." Anagrams.net. STANDS4 LLC, 2025. Web. 12 Mar. 2025. <https://www.anagrams.net/psychological%20dependence>.

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